SELANK

Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a synthetic heptapeptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences as an analogue of tuftsin (Thr-Lys-Pro-Arg), a naturally occurring tetrapeptide fragment of IgG with immunomodulatory properties.
GABAergic Neurotransmission Research
Preclinical research in rodent models has examined Selank's interactions with GABAergic neurotransmission, including its effects on GABA-A receptor expression and subunit composition in hippocampal and cortical regions.
BDNF and Neurotrophin Research
Research has examined Selank's effects on BDNF expression in rodent brain tissue. Studies have documented changes in BDNF mRNA levels in hippocampal regions following Selank administration in experimental models.
Enkephalin and Opioid Peptide Research
A notable area of Selank research involves its interactions with enkephalin-degrading enzymes. Studies have examined its capacity to inhibit enzymes responsible for enkephalin breakdown in experimental models.
• Semenova TP et al. (2010). Selank and tuftsin influence on the behavior of rats in the open field test. Experimental and Clinical Pharmacology, 73(7), 24–27.

• Molecular Weight: 751.86 g/mol
• CAS Number: 129954-34-3
• Sequence / Structure: Thr-Lys-Pro-Arg-Pro-Gly-Pro (7 aa heptapeptide — tuftsin analogue)
• Form: Lyophilized powder
• Purity: ≥99% (HPLC verified)
• Storage: Per Certificate of Analysis

Every batch is independently tested by Brown Institute of Biomolecular Research. It confirms compound identity and verified purity of 99% or higher.

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